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NATIONAL OPEN UNIVERSITY OF NIGERIA

UNIVERSITY VILLAGE, PLOT 91, CASDASTRAL ZONE, NNAMDI AZIKIWE EXPRESS WAY, JABI, ABUJA.
FACULTY OF SCIENCES
JUNE/JULY 2013 EXAMINATION

COURSE CODE:                                                                              BIO301

COURSE TITLE:                                                                             Genetics II

DURATION:                                                                                     2 Hours

INSTRUCTIONS:                                                                            Answer question 1 and any other 4 questions

 

Q1.a     (i)        What do you understand by the term mutagens?

            (ii)       Describe the mode of action of the following mutagens:

(a)       Nitrous acid               (b)       A base Analog            (c)       UV light

      b.   (i)        Define genetic transfer.

(ii)       How can you tell if there are any mutant colonies in a culture?

 

Q2.a     (i)        Define population cytogenetics.

            (ii)       Discuss the genetic significance of deletion.

      b.   (i)        Mention the goals of population genetics.

            (ii)       Describe the different types of duplications, and list their effects.

 

Q3.a     (i)        What do you understand by the term pedigree?

            (ii)       Write short notes on the following:

(a)       Karyotype      (b)       Codominance             (c)       dosage compensation.

      b.   Explain why sickle cell anemia is regarded as a heritable disease.

 

Q4.a     (i)        Enumerate the role of structural chromosomal aberrations in plant breeding

(ii)       Describe the mode of occurrence of the different types of inversions you know.

(iv)      Polyploids are of significant effects. Discuss

 

Q5.a     (i)        How do genes determine sex?

            (ii)       Describe the structure of protein.

      b.   (i)        What are the components of a ribosome?

(ii)       Describe the various stages involved in transcription.

 

Q6.a     (i)        What do you understand by the term paralogous?

            (ii)       Briefly discuss the origin of polyploidy.

      b.   (i)        List the characteristics of X-linked traits

            (ii)       Write short notes on the following:

(a)       silent mutation          (b)       missence mutation and

(c)       point mutation


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