NATIONAL OPEN UNIVERSITY OF NIGERIA

UNIVERSITY VILLAGE, PLOT 91, CASDASTRAL ZONE, NNAMDI AZIKIWE EXPRESS WAY, JABI, ABUJA.
FACULTY OF SCIENCES
JANUARY 2013 EXAMINATION

COURSE CODE:           BIO 305

COURSE TITLE:            MOLECULAR BIOLOGY

TIME ALLOWED:         2 Hours

 ANSWER ANY FOUR QUESTIONS

 1ai.     What is molecular biology?

    ii.     Outline the relationship of molecular biology to other biological science

   bi.     What do you understand by the term chromosomes?

    ii.     Ecsherichia coli is useful in molecular biology, discuss.

2ai.      What is nucleic acid hybridsation?

   ii.      Write short notes on the following:

(i)         a cistron

(ii)        muton

(iii)       recon

bi.        List the major components of a nucleus

 ii.        Describe how hormones control gene-expression

3ai.      Define DNA.

   ii.      Write short notes on the following:

1. 1. t RNA
   2. r RNA
   3. m RNA

  bi.      Define gene-expression.

   ii.      Outline the characteristics of genetic code.

4ai.      Describe the various steps involved in the process of chain elongation stage during protein synthesis..

   ii.      What is DNA sequencing?

b.       Briefly describe any two methods for determining DNA sequences.

5ai. What do you understand by the term catabolism?

      ii. Outline the important features of glycolysis.

 bi Enumerate the stages involved in the breakdown of glucose.

   ii. Describe the process of oxidative phosphorylation

 6ai. Outline the importance of genes in heredity.

    ii. Write short notes on termination and the kreb citric acid cycle

   bi. Highlight the roles of DNA and RNA

      ii. Describe the central dogma