NATIONAL OPEN UNIVERSITY OF NIGERIA

UNIVERSITY VILLAGE, PLOT 91, CASDASTRAL ZONE, NNAMDI AZIKIWE EXPRESS WAY, JABI, ABUJA.
FACULTY OF SCIENCES
JUNE/JULY 2013 EXAMINATION

COURSE CODE:           BIO305

COURSE TITLE:            MOLECULAR BIOLOGY

TIME ALLOWED:         2 HOURS

INSTRUCTION: ANSWER ANY FOUR QUESTIONS

 1ai.     Outline the importance of genes in heredity.

    ii.     Write short notes on termination and the kreb citric acid cycle

  bi.      Highlight the roles of DNA and RNA

   ii.      Describe the central dogma

2ai.      What is nucleic acid hybridization?

   ii.      Write short notes on the following:

(a) a cistron

(b) muton

(c) recon

 bi.       List the major components of a nucleus

  ii.       Describe how hormones control gene-expression

3ai.      Describe the various steps involved in the process of chain elongation stage during protein synthesis.

    ii.     What is DNA sequencing?

  b.       Briefly describe any two methods for determining DNA sequences.

4ai.      What is molecular biology?

   ii.      Outline the relationship of molecular biology to other biological science

bi.        What do you understand by the term chromosomes?

ii.         Ecsherichia coli are useful in molecular biology. Disc

5a.          Define DNA.

  b.       Write short notes on the following:

(i) tRNA

(ii) rRNA

(iii) mRNA

ci.        Define gene-expression.

ii.         Outline the characteristics of genetic code.

6ai.      What do you understand by the term catabolism?

   ii.      Outline the important features of glycolysis.

  bi.      Enumerate the stages involved in the breakdown of glucose.

   ii.      Describe the process of oxidative phosphorylation