NATIONAL OPEN UNIVERSITY OF NIGERIA

UNIVERSITY VILLAGE, PLOT 91, CASDASTRAL ZONE, NNAMDI AZIKIWE EXPRESS WAY, JABI, ABUJA.
FACULTY OF SCIENCES
MARCH/APRIL 2015 EXAMINATION

COURSE CODE:                  BIO 305

COURSE TITLE:                 MOLECULAR BIOLOGY

TIME ALLOWED:               2 Hours

INTRUCTION: Answer question ONE (1) and any other THREE (3) questions

1a. Describe how hormones control gene-expression. (8 marks) 

  b. Outline the characteristics of genetic code. (7 marks) 

  c. List the major components of a nucleotide. (3 marks)

  d. Account for the relationship of molecular biology to other biological sciences. (7 marks)

2a. List the stages involved in the breakdown of glucose. (4 marks)

  b. What is nucleic acid hybridzation? (2 marks)

  c. Write  short notes on the following:

       (i) m RNA (3 marks)

       (ii) t RNA (3 marks)

      (iii) r RNA  (3 marks)

3a. Describe the process of oxidative phosphorylation. (7 marks)

 b. Give an account of the central dogma. (8 marks)

4a. Outline the important features of glycolysis. (6 marks)

 b. Escherichia coliis useful in molecular biology, Discuss. (9 marks)

5a. Describe the structure of a DNA. (8 marks)

 b. Account for the relationship of molecular biology to other biological sciences. (7 marks)

6a. What do you understand by the term catabolism? (3 marks)

 b. Give a detailed description of any two methods used for determining DNA sequences. (12 marks)